Low/Intermediate PCa Video Chat, January 12, 2026

Low/Intermediate PCa Video Chat, January 12, 2026

AnCan is grateful to the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics, and Foundation Medicine. WELCOME all to our newly recorded Low/Intermediate Prostate Cancer Group. To receive notice when new recordings are posted, either follow us on this YouTube Channel or sign up to our Blog via https://ancan.cyberoptik.co/contact-us/ – check New Blog box.
Join our other free and drop in groups:
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.cyberoptik.co/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime!
Editor’s Pick: Using DECIPHER genomic testing to assess cancer agressiveness. (bj) Topics Discussed Cancer discovery following an aquablation procedure for an enlarged prostate; post-procedure PSA and MRI testing to monitor remaining cancer; comparing transrectal and transperineal biopsy safety and access; importance of consulting genitourinary oncologists at major centers; using specialists like Dr. Epstein for pathology second opinions; weighing active surveillance against the risk of cancer progression; discussion of MR LINAC, proton, and photon radiation technologies; using PSMA PET scans to detect potential lymph node involvement; selecting high-volume urban medical centers over smaller clinics; using DECIPHER genomic testing to assess cancer agressiveness. Chat
Stuart sent a chat · 8:01 PM Dr. Ming Zhou – Mt Sinai Health System  Email: Ming.zhou@mountsinai.org      Telephone: (212)241-8881 Stuart sent a chat · 8:02 PM Dr. Jonathan Epstein – https://advanceduropathology.com/  Tel:516-760-2037    jepstein@imppllc.com Steve in Malaysia sent a chat · 8:39 PM What is an AI MRI? Steve in Malaysia sent a chat · 8:42 PM ok AnCan – rick sent a chat · 8:48 PM Proton vs Photon  https://ascopubs.org/doi/abs/10.1200/JCO.23.01604?md5=efb3c3159aa147415d4f2ded3334efa3&cid=DM16707&bid=358786211 Gil Solomon sent a chat · 8:52 PM Have to sign off for dinner. Steve in Malaysia sent a chat · 8:57 PM I need to finish packing for trip from Penang to California shortly so would appreciate some quick questions. AnCan – rick sent a chat · 9:07 PM Check our AnCan video with Dr. Scholz  on Prostate Snatchers. https://ancan.cyberoptik.co/the-prostate-snatchers-still-lurking/ Steve sent a chat · 9:14 PM Carter AnCan – rick sent a chat · 9:25 PM Steve – CHEK2 may in fact make you more sensitive to RT. Check with Dr. Kivel Steve sent a chat · 9:28 PM Thanks Rick! David in Portland, OR sent a chat · 9:39 PM “Most mutations in DNA repair genes such as BRCA1/2, PALB2, CHEK2, and RAD50/51 mutations do not increase radiation-induced cancers or radiation toxicity. BRCA1/2, PALB2, CHEK2, and RAD50/51 mutations should not affect radiation therapy decisions.” Source: https://www.redjournal.org/article/S0360-3016(19)33530-8/fulltext I also communicated with Joanne Wiedhaas last year directly about this topic, and she confirmed the above quote from the International Journal of Radiation Oncology. Govinda – India sent a chat · 9:41 PM Daily dosage of  Viagra was 5 mg daily. Of course this varies from person to person. Steve in Malaysia sent a chat · 9:42 PM I’m going to sign off… thanks guys David in Portland, OR sent a chat · 9:42 PM 5 milligrams/day of tadalafil/Cialis gives me significant heartburn. Anybody else have this problem? Any fixes other than stopping the Cialis? AnCan – rick sent a chat · 9:51 PM Interesting David….    the general opinion is that HRR mutations make you more sensitive to RT toxicity. I think there’s a fair amount of literature. Stuart sent a chat · 9:56 PM Dr James Hu – Weill Cornell Stuart sent a chat · 9:56 PM Dr Nagar – MSKCC Stuart sent a chat · 9:57 PM or Michael J. Zelefsky, MD – NYU Langone Steve sent a chat · 10:17 PM Thanks David!