Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 17, 2025
AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics and Foundation Medicine. Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants. AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence. AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team. AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.cyberoptik.co/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.cyberoptik.co/contact-us/ Join our other free and drop in groups: Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.cyberoptik.co/men-speaking-freely/ Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.cyberoptik.co/veterans/ Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room Editor’s Pick: Assessing recurrence and IDC-P repeat this week.Topics Discussed
Signs of recurrence after 8 years; lymphedema and RT; does Newbie understand his proposed RT – is it optimal?; signs of BRCA2 recurrence post RP; doublet or triplet for denovo Mx Gent with IDC-P; explaining types of HT treatment; likely PSMA negative Gent challenged to confirm recurrence; PSA spike & fall for IHT man; fatigue after ARSI is added; estradiol supplement experience; pushing exercise helps mitigate HT; IDC-P teatment challenge – RP vs RT; bisphosphonate vs denosumab as bone strengthenerChat
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Larry (Alaska)sent: 6:17 PMWas there a decipher test? indicating aggressiveness?
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Larry (Alaska)sent: 6:24 PMI wonder how old those NIH studies Barbara and Joe are reading?
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Eric James; Tyler TXsent: 6:29 PM
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Eric James; Tyler TXsent: 6:31 PMThe higher rates of lymphedema are after pelvic irradiation following lymph node dissection
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AnCan–John Asent: 6:31 PMThx Eric
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Bob Y. Los Angelessent: 6:34 PMQuestion: for a Decipher Prostate Test… how do I get that genomic test? Does my doctor order it or what?
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AnCan – ricksent: 6:35 PMSandy Liu https://www.cityofhope.org/sandy-liu
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Eric James; Tyler TXsent: 6:35 PMBob Y. Yes, generally done from your biopsy tissue
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Jim Marshall, Veteran, Alexandria, VAsent: 6:35 PMThere is Germline test and Somatic Test nothing to do with Decipher. Jim
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Bob Y. Los Angelessent: 6:38 PMThanks. I’ll ask my urologist to run the Decipher test from my biopsy tissue.
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Jeff Marchi – San Franciscosent: 6:43 PMget genetic test free here
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Jeff Marchi – San Franciscosent: 6:43 PM
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Luther Blakesent: 6:46 PMhave to run gents, have a good evening
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AnCan – ricksent: 5:57 PMGoTo technical support 877 582 7011
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AnCan–John Asent: 6:48 PMming.zhou@mtsinai.org, or https://profiles.mountsinai.org/ming-zhou OR
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AnCan–John Asent: 6:49 PMadvanceduropathoogy.com 516 280 7930
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Jeff Marchi – San Franciscosent: 6:53 PMwhile that email may work I got a different address
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Jeff Marchi – San Franciscosent: 6:53 PMSend an email to Ming.zhou@mountsinai.org to inquire about a second opinion and ask for his specific instructions for the process.
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Jim Stewart Reno, NVsent: 7:07 PMhave to sign off, thanks all and have a good night
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Jon McPhee Torontosent: 7:33 PMHave to go. Thanks for the meeting.
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Larry (Alaska)sent: 7:37 PMAI just told me that 1- micro-ultrasound does not require a contrast dye and uses equipment that is more accessible than MRI. 2- Other than that, they seem to be seen as complementary rather than competing. MRI is better at detecting some lesions and micro-ultrasound better at others.
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Stan Friedmansent: 7:48 PMSorry. Need to sign off. Will update on my pluvicto treatments next week. Thanks.
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Jim Marshall, Veteran, Alexandria, VAsent: 7:53 PMChocolate is a veggie!!!!!! Jim
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TonyFigsent: 7:53 PMRick will get a 3 knot boost when rowing with caffeine
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Stsent: 7:56 PMmy experience has been that the fatigue comes mainly from lack of estrogen, not from the lack of T. An E2 patch helped me enormously
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Bob Y. Los Angelessent: 7:57 PMI had a couple of short questions, but I have to leave now. I’ve had an MRI and a biopsy, Gleason 4+5. I’m waiting to get a PET Scan on Dec 5th. I was hoping to get the PET earlier and so I made an appt with a urologic oncologist, Timothy Daskivich for a 2nd opinion on Nov 26th. Now I’ll be going to see him without being able to show him the PET results. I’m wondering if that appt is still valuable.
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Barbara and Joesent: 7:59 PMwhy do you have to take something as toxic as prednisone with abiraterone?
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Don Rogerssent: 8:00 PMgot to go
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Eric James; Tyler TXsent: 8:00 PMBarbara and Joe: side effects of abiraterone. Your body stops producing cortisol on abiraterone so it needs to be replaced with something similar.
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AnCan–John Asent: 8:00 PMBarbara and Joe the body absolutely needs the corticosteroid.
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Jim Marshall, Veteran, Alexandria, VAsent: 8:01 PMAbi stops the Adrenal Glands which makes Cortisol. Presidnsone makes the Cortisol.
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Jim Marshall, Veteran, Alexandria, VAsent: 8:02 PMOne needs Cortisol. Jim Marshall
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AnCan – ricksent: 8:10 PMEstradiol seminar w. Steve S https://ancan.cyberoptik.co/talking-estradiol-e2-for-recurrent-and-advanced-prostate-cancer/
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Keith H. (southern Oregon)sent: 8:15 PMthanks for all this, I got to go, but grateful for expertise and this group.
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Thomas Maticasent: 8:21 PMShort update. Can wait till next meeting. Got to run. Thanks everyone.
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Barbara and Joesent: 8:23 PMI hope it’s a low dose of predisone — it just about killed my mother with her rheumatoid arthritis.
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Jim Marshall, Veteran, Alexandria, VAsent: 8:23 PM5mg of Prednisone is used. Jim M
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Jim Marshall, Veteran, Alexandria, VAsent: 8:24 PMAlthough once you stop it one still should taper off versus Cold Turkey. Jim
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Steve Whitesent: 8:28 PMHave to drop…thanks again
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Alfredo in Houston, TXsent: 8:35 PMI must drop off now, thank you everyone; stay well.
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Mark Nsent: 8:42 PMThanks!!
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Barbara and Joesent: 8:43 PMthanks so much everybody.